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By Ottaviano Bon, John Withers

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Recording retrieved data electronically Size ● I included 763 randomised controlled trials in my systematic review. The paper pile of single data retrieval sheets would weigh nearly 4 kg and occupy a volume of 5 litres. My flash drive weighs a few grams and fits on a key ring. I extracted data from each study into between 40 and 100 columns in Excel (see below) – my writing would have to be very small to fit this information on one side of A4. I also needed to share the data retrieval forms with colleagues who verified the extracted data: it is expensive to transport 4 kg by post to another country.

There has been very little empirical research on how different methods of data retrieval and storage affect the results of systematic reviews. Most research has focussed on variables in the early part of the process, such as blinding data extractors to the authors, institute and publishing journal of each trial. Because of the paucity of evidence I have written a pragmatic chapter based upon my own experience as an author and editor of Cochrane systematic reviews. Therefore you should not accord my conclusions with the same weight you would give to conclusions in other chapters that are based upon more evidence.

RCT: randomised controlled trial 3 Inclusion and exclusion criteria You must verify that you can use the results of a study to answer your question (before you expend time extracting data). g. randomly allocated placebo-controlled trials). 4 Intervention Record the number of participants allocated to each intervention, not the number assessed (intention-to-treat analysis). Verify that the controls are adequate enough to be categorised as placebo. 1 Dichotomous outcomes – “it did or did not happen” – are recorded as proportions; the number of participants experiencing an outcome divided by the number allocated to that intervention.

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